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Itchy - Karen's Musings
Random Rambling
estherchaya
estherchaya
Itchy
So I started getting weekly progesterone injections (17P) to reduce the risk of pre-term labor this go around.   I'm not new to progesterone injections, they don't scare me, and honestly they don't even hurt me.  I can't for the life of me figure out why a nurse has to come out every week to administer the injections... it's not like I've never done it before.  (The nurse is here anyway, because of the PICC line, but even if she weren't already coming, they'd send her out to just doe the injections if that's all that was going on with me)

I've had about 100 progesterone in oil injections and never had any issue.  Despite dire warnings about the sesame oil that it is in, I never reacted in any way, other than some discomfort at the injection site as the PIO got absorbed into the surrounding muscle. 

The 17P injections aren't quite the same as the PIO I used, but the 17P is also progesterone in oil.  And now?  I am itching like MAD at every injection site.  It's worst very shortly after the injection is given, and it starts to fade toward the end of the week, and then when I get the next injection, it's all itchy at that site, as well as all the other injection sites that have been used.  It is maddening.

Fortunately, this is but a minor issue for the moment, but it's still annoying. 

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Comments
From: atimesif Date: January 28th, 2010 04:18 am (UTC) (Link)
Sorry to hear about the itching. Can you take a progesterone suppository instead?
estherchaya From: estherchaya Date: January 28th, 2010 12:04 pm (UTC) (Link)
Not really - it doesn't have the same effect. This isn't quite the same progesterone formulation as that which you take after transfer in IVF. I think the dose is higher, and I'm not sure about all the other details.
mindycl From: mindycl Date: January 28th, 2010 05:02 am (UTC) (Link)
I took 17P from 19w til 36w. I gave myself the shot actually - and Shimie would pull his shirt up and pretend to give himself a shot. lol.
estherchaya From: estherchaya Date: January 28th, 2010 12:05 pm (UTC) (Link)
I have no issue giving myself the shot. The home health care company will have nothing to do with it. As far as I can figure, the only doctors who give their patients any credit for having a brain in their head and for being capable of such things are reproductive endocrinologists).
rlitterst From: rlitterst Date: January 28th, 2010 01:22 pm (UTC) (Link)
Steve gave me my first progesterone shot last night. Thankfully it wasn't bad at all!

I hope the itching stops for you soon!!
estherchaya From: estherchaya Date: January 28th, 2010 03:23 pm (UTC) (Link)
I don't find the injections themselves problemmatic. I'm, fortunately, not phased by needles. I never had any sort of itching or anything with the PIO after IVF. This progesterone is somewhat different, but still in sesame oil (or similar), and the itching is ridiculous!
mrn613 From: mrn613 Date: January 28th, 2010 01:26 pm (UTC) (Link)
You can get it compounded in cottonseed oil if you are so inclined.
estherchaya From: estherchaya Date: January 28th, 2010 03:44 pm (UTC) (Link)
yeah, I know. Though I've never seen anyone do that with the 17P - just with the PIO used after IVF (they're slightly different, but the difference eludes me, despite Seth's best efforts to explain it to me). I'm not too inclined to get it specially compounded at this point, because it's itchy, but it's not like there are any welts or anything like that. This pregnancy seems to have made my skin super sensitive to EVERYTHING. I've never reacted to adhesive before, but I get huge welts and inflammation from the adhesive on the PICC dressing (we've tried several kinds - and have resorted to gauze dressing for 2 days, tegaderm for 5 days for the time being and have switched from chloroprep to betadine which helps a little). Until I took a course of IV steroids in December/early January, my whole body itched and itched unrelentingly (my skin was RAW from scratching in my sleep), but fortunately that went away on the steroids and hasn't returned.

And now this odd reaction to the 17P. I mean, it's a common reaction, but not normal for me.

I'm hoping that somehow my immune system returns to normal after I deliver this baby. I know that pregnancy is immunosuppressant by itself, so it's not out of the realm of possibility that all these new reactions of mine are transient.
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